Your mouse and keyboard will also require occasional cleaning. On some keyboards, you can pop off the key caps on your keyboard to get at dirt and hair between the keys. You can also remove your mouse ball to clean it and the rollers inside the mouse. Use a commercial spray cleanser applied to a cotton swab to clean your keyboard and mouse.
A new product that I've used and had good luck with is Viatek Cyber Clean High Tech Cleaning Compound- Single Pack. A gel type cleaning compound that you actually press into keyboards and other devices and it lifts the dirt away. Removing this dust, dirt, and grime from your computer system is an important step in prolonging the life of any computer system. The cleaner you keep it, the longer it will last.